Tuesday, 06.09.2022 – MHC Antigen Processing and Purification

(Chairs: Jenn Abelin, Wei Wu)

• From 11 am Registration

• 13:00-13:15 Opening Remarks

• 13:15-14:15 Keynote Lecture: Tim Elliott, Integrating Computational Modelling and Experimental Biology to Improve Tumour Antigen Discovery

• 14:15-15:00 Lecture Wayne Paes, The Utility of Immunopeptidomics in Unravelling Complexities of the Antigen Processing and Presentation Pathway

• 15:00-15:30 Coffee Break

• 15:30-16:00 Lecture Nicola Ternette, Sample preparation: A Critical Review

• 16:00-18:00 Flash Talks + Poster Session 1

• From 18:30 Drinks Reception and Gala Dinner at New College

Wednesday, 07.09.2022 – LC-MS: Methods and Applications

(Chairs: Michal Bassani-Sternberg/Nicola Ternette)

• 09:00-10:00 Keynote Lecture: Jennie Lill, The Importance of Immunopeptidomics in Drug Discovery & Development @ Genentech

• 10:00-10:45 Lecture Jenn Abelin, MS Methods & Instrumentation

• 10:45-11:15 Coffee Break

• 11:15-12:00 Lecture Pouya Faridi, The Use of TMT and DIA in Immunopeptidomics

• 12:00-13:30 Lunch

• 13:30-14:15 Lecture Wei Wu, Chromatography and Parallel Reaction Monitoring for Antigen Discovery

• 14:15-15:00 Q&A with all Faculty

• 15:00-15:30 Coffee Break

• 15:30-17:30 Flash Talks + Poster Session 2 (Drinks Reception from 5 pm)

• From 17:30 Sponsor Networking event

Thursday, 08.09.2022 – Data Analysis

(Chairs: Pouya Faridi/Annika Nelde)

• 9:00-10:00 Keynote Lecture: Tony Purcell, Immunopeptidomics: Challenges, controversies and moving to the clinic

• 10:00-11:00 Lecture Karl Clauser, Challenges and Solutions for the Confident Interpretation of MS/MS Spectra in Immunopeptidomics

• 11:00-11:30 Coffee Break

• 11:30-12:15 Lecture Krystel Vincent, Building Personalized Databases for the Identification of Tumor-Specific Antigens

• 12:15-13:30 Lunch

• 13:30-14:15 Lecture Mathias Wilhelm, Improving Mass Spectrometry-based Immunopeptidomics by Utilizing Accurate Peptide Property Predictions

• 14:15-15:00 Q&A with all faculty

• 15:00-15:30 Coffee Break

• 15:30-16:30 Keynote Lecture: Pierre Thibault, Proteogenomics Uncovers Tumor-specific Antigens from Canonical and Non-canonical Genomic Regions

• 16:30-18:30 Flash Talks + Poster Session 3 (Drinks Reception from 5 pm)

Friday, 09.09.2022 – Translational Immunopeptidomics

(Chair:Krystel Vincent)

• 09:00-09:30 Lecture Annika Nelde, Immune Recognition of Peptides - Don't Forget the T Cell Response

• 09:30-10:30 Lecture Juliane Walz, Clinical Translation of Peptide-based Immunotherapy

• 10:30-11:00 Coffee Break

• 11:00-12:00 Keynote Lecture: Olivera Finn, Tumor Antigens, Immunosurveillance and Preventative Cancer Vaccines

• 12:00-12:30 Poster Awards

• 12:30-14:00 Lunch and Departure